WebApr 6, 2024 · MYCN is a canonical proto-oncogene basic helix-loop-helix transcription factor that is mainly restricted to the migrating neural crest ( 11) and governs cell growth and differentiation during embryonic stages ( 12 ). Amplification of the MYCN locus was first observed in human neuroblastoma ( 13 ). WebWe utilized two dif- ferent web-based tools miRDB and TargetScanHuman 7.2 for miRNA target gene prediction; the target genes only enrichedin the twodatabases wereselected as putative target genes[15,16].TheVenndiagramwasappliedtovisualizethe overlapping DEGs of DEM target genes and DEGs in COAD …
Detection of features predictive of microRNA targets by ... - PubMed
WebJul 21, 2024 · Quantitative real-time polymerase chain reaction was performed to determine the expression level of miR-198 in fresh RCC tissues. Furthermore, the target … Webthe TargetScanHuman 7.2 database33, with context++ score < 0.4 and percentile >0.99 as previously - applied34. Then UTR and enhancer associated genes were extracted from annotations in UTRdb database30 and EnhancerAtlas database35. Genes were functionally annotated using Gene Ontology (GO) huntsman cockermouth
Properties of REST-associated miRNA-target gene pairs (REST) …
WebJun 1, 2024 · Prediction of mRNA targets Two established miRNA target prediction programs (starBase and TargetScanHuman 7.2) were used to predict the putative … WebMar 9, 2024 · And we utilized two different web based tools, miRDB and TargetScanHuman 7.2, to screen the target genes of miRNAs. The target genes only enriched in two databases could be selected as putative target genes for the next analysis. Gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analysis huntsman coatings